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This is a randomized, parallel, open label Phase II single-arm window trial to assess the clinical and biological effects of neoadjuvant abemaciclib in patients with HPV-negative head and neck squamous cell carcinoma (HNSCC).

The Division of Trauma and Acute Care Surgery of the George Washington University is the academic arm of the Center for Trauma and Critical Care (CTACC) of the George Washington University Hospital.

Elham Bayat, MD, is an assistant professor of neurology and Director of the ALS Clinic at The George Washington University & The GW Medical Faculty Associates. Dr. Bayat is triple board-certified in neurology, electrodiagnostic medicine, and neuromuscular medicine. She received her medical…

This project is a prospective, observational study aimed to predict bleeding using hemoglobin trends measured non-invasively in patients undergoing elective cesarean delivery at the George Washington University Hospital.

To develop maternal-fetal PBPK models for drugs commonly taken by pregnant women including Labetalol, Sertraline, Famotidine, and to validate these models with blood concentrations from maternal and umbilical cord blood samples.

To evaluate the relative sensitivity and specificity of HPV methylation testing from self-collected compared to clinician-collected samples for detection of cervical precancer.

The primary objective of the study is to assess the clinical utility of combining NIPT-based zygosity measurements with ultrasound chorionicity assessments for the management of twin pregnancies. 

Randomized Phase II/III Trial of Adjuvant Radiation Therapy With Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck