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Shabnam Samankan MD, is an assistant professor of gynecologic, breast and ENT pathology in the Department of Pathology at George Washington University (GW) and the Division Chief of Head & Neck and Endocrine Pathology. Prior to joining GW, Dr. Samankan completed a subspecialty fellowship…
Rebecca Yee, Ph.D, D(ABMM) is the Chief of Microbiology and Assistant Professor in the Department of Pathology at George Washington University.
Primary objective: The primary objective of the study is to compare disease-free survival (DFS) of patients with high-risk cutaneous squamous cell carcinoma (CSCC) treated with adjuvant cemiplimab, versus those treated with placebo, after surgery and radiation therapy (RT).
Primary Outcome Measure: Maximum tolerated dose of nivolumab [Time Frame: 56 days]
Will be defined as the starting dose level at which 1/6 subjects experience dose limiting toxicity (DLT) with the next higher dose having at least >= 2 participants encountering DLT. Toxicity data will be…
Have at least 20 nodules of approximately 0.5 to 2 cm. The nodules must be pruritic and present on at least 2 different anatomical locations (not be localized), involve the extremities, with extensor extremity involvement greater than the flexor extremity involvement. Nodules on the head (face and…