Clinical Trials
The GW Medical Faculty Associates is proud of its physician scientists and their commitment to medical research. These clinical studies are designed to add to the medical knowledge base and relate to the treatment, diagnosis, and prevention of diseases or conditions.
Our overall goal at Mommy&Me is to partner with former patients, moms with experience giving birth in D.C. and other members of low-income Black communities to develop and test different approaches to overcome obstacles and achieve health equity by providing effective mental health screening…
Primary Objective: to compare the non-inferiority of bilateral salpingectomy (BLS) with delayed oophorectomy to bilateral salpingo-oophorectomy (BSO) to reduce the risk of ovarian cancer among women with deleterious BRCA1 germline mutations.
Primary Outcome Measures: Rate of Progression to Prostate Cancer (PCa) [Time Frame: 24 months]
Number of participants with clinical progression defined as a composite outcome on repeat prostate biopsy >33% of biopsy cores positive for cancer or >50% of any biopsy tissue core positive…
CASPAR - A Phase III Trial of Enzalutamide and Rucaparib as a Novel Therapy in First-line Metastatic Castration-Resistant Prostate Cancer
Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Lirentelimab in Adult Subjects with Moderate-to-Severe Atopic Dermatitis Inadequately Controlled by Topical Treatments
The purpose of this research study is to better understand how different types of mental health care can help pregnant women and mothers with infants under the age of 1 feel less stressed. Stress, depression, and/ or anxiety that occurs during pregnancy or after having a baby can affect can have…
Randomized Phase II/III Trial of Radiation With High-Dose Cisplatin (100 mg/m2) Every Three Weeks Versus Radiation With Low-Dose Weekly Cisplatin (40 mg/m2) for Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)
To assess the role of administering TXA pre-cord clamp in three different routes of administration (IV push, IM and IV infusion) for preventing postpartum hemorrhage.
This study will include collecting blood samples to send to the lab on patients who are found to be at higher risk for transfusion using both inpatient nursing evaluation and validate our prediction model.
The purpose of this study is to assess the effect of reldesemtiv versus placebo on functional outcomes in patients with ALS.
The objective of the TRIUMPH study (Preventive Treatment of Migraine: Outcomes for Patients in Real-World Healthcare Systems) is to evaluate the real-world effectiveness of Emgality, in comparison to other preventive treatments for migraine, among people receiving routine medical care who are…
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2…
This project is a prospective, observational study aimed to predict bleeding using hemoglobin trends measured non-invasively in patients undergoing elective cesarean delivery at the George Washington University Hospital.
To develop maternal-fetal PBPK models for drugs commonly taken by pregnant women including Labetalol, Sertraline, Famotidine, and to validate these models with blood concentrations from maternal and umbilical cord blood samples.
To evaluate the relative sensitivity and specificity of HPV methylation testing from self-collected compared to clinician-collected samples for detection of cervical precancer.