Clinical Trials

The GW Medical Faculty Associates is proud of its physician scientists and their commitment to medical research. These clinical studies are designed to add to the medical knowledge base and relate to the treatment, diagnosis, and prevention of diseases or conditions.

The purpose of this research study is to better understand how different types of mental health care can help pregnant women and mothers with infants under the age of 1 feel less stressed. Stress, depression, and/ or anxiety that occurs during pregnancy or after having a baby can affect can have…

Randomized Phase II/III Trial of Radiation With High-Dose Cisplatin (100 mg/m2) Every Three Weeks Versus Radiation With Low-Dose Weekly Cisplatin (40 mg/m2) for Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)

This trial will compare the safety and immune response of different doses and different administration methods (intradermal vs. subcutaneous) of the approved monkeypox vaccine (JYNNEOS).

To assess the role of administering TXA pre-cord clamp in three different routes of administration (IV push, IM and IV infusion) for preventing postpartum hemorrhage.

This study will include collecting blood samples to send to the lab on patients who are found to be at higher risk for transfusion using both inpatient nursing evaluation and validate our prediction model.

The purpose of this study is to assess the effect of reldesemtiv versus placebo on functional outcomes in patients with ALS.

The objective of the TRIUMPH study (Preventive Treatment of Migraine: Outcomes for Patients in Real-World Healthcare Systems) is to evaluate the real-world effectiveness of Emgality, in comparison to other preventive treatments for migraine, among people receiving routine medical care who are…

The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2…

A Multicenter, Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy and Safety of 2 Dose Regimens (Intravenous/Subcutaneous and Subcutaneous) of TEV-48125 Versus Placebo for the Prevention of Chronic Cluster Headache.

This project is a prospective, observational study aimed to predict bleeding using hemoglobin trends measured non-invasively in patients undergoing elective cesarean delivery at the George Washington University Hospital.

To develop maternal-fetal PBPK models for drugs commonly taken by pregnant women including Labetalol, Sertraline, Famotidine, and to validate these models with blood concentrations from maternal and umbilical cord blood samples.

To evaluate the relative sensitivity and specificity of HPV methylation testing from self-collected compared to clinician-collected samples for detection of cervical precancer.

The primary objective of the study is to assess the clinical utility of combining NIPT-based zygosity measurements with ultrasound chorionicity assessments for the management of twin pregnancies. 

Randomized Phase II/III Trial of Adjuvant Radiation Therapy With Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck

A Phase1, First-in-Human, Open-Label, Dose Escalation and Expansion Study of CUE-101 Monotherapy in Second Line or CUE-101 Combination Therapy With Pembrolizumab in First Line Patients With HPV16+ Recurrent/Metastatic HNSCC KEYNOTE-A78